Season 2 of Preacher is a genre-bending thrill ride that follows West Texas preacher Jesse Custer, his badass ex-girlfriend Tulip and an Irish vampire named Cassidy as they embark on a road trip to find God.

Jesse, Tulip and Cassidy hit the road in search of God, and quickly realize they're being stalked by a killer cowboy from Hell.

Jesse, Tulip and Cassidy find Fiore working as a magician in Las Vegas, and try to convince him to answer their questions about the Cowboy.

While Jesse searches jazz clubs in New Orleans for God, Cassidy finds a play for them to crash. However, Tulip soon realizes that she can't escape her past. Meanwhile, Eugene suffers in Hell.

Jesse spots the actor who played God in an infomercial and tracks him down. Meanwhile, Tulip meets with Viktor.

As Jesse considers what to do with Viktor, he and Tulip remember the past after they lost the baby.

Jesse and his friends discover what the Cowboy wants, and are forced to deal with him when he captures Denis.

Tulip has nightmares of the Cowboy's touch, and finds a unique way to deal with them. Meanwhile, Jesse seeks out a doomsday preacher for advice on selling 1% of his soul, and the origin of Herr Starr's entry into the Grail is revealed.

While Cassidy considers what to do with Denis, Tulip spackles the bulletholes that the Cowboy left in the walls. Meanwhile, Jesse goes to a video store to try and determine whose gun was used to kill Mark Harelik.

After the Grail's first assault on Jesse and his friends fail, they unleash BRAD. Meanwhile, Tulip's PSD continues to get worse, and Denis revels in his new health.

Jesse finally meets the Messiah face-to-face, but he isn't what Jesse expects. Meanwhile, Lara works to create a divide between Tulip and Jesse, while Denis gives in to his new appetites.

Jesse realizes where God is and goes to find Him, but discovers that He is already gone. Meanwhile, Hitler shows Eugene a way out of Hell, and Tulip resolves to destroy the Cowboy's guns.

After the Grail frees the Cowboy, he comes looking for Jesse. Meanwhile, Eugene comes to terms with his past so that he and Hitler can escape Hell.

Starr puts Jesse on the path to messiahdom. Meanwhile, Cassidy deals with Denis and Tulip finds out who has been spying on them.