Gaius Claudius Glaber is dead. Many months have passed since his defeat and the rebel army, led by Spartacus and his generals Crixus, Gannicus, and Agron, continue to amass victories over Rome. With the rebel numbers swelling to thousands of freed slaves, Spartacus is more determined than ever to bring down the entire Roman Republic. Following Ashur's death, Naevia and Crixus fight as one. Together, the rebels engage in one bloody skirmish after another and prepare for the inevitable: a full out war with Rome. The Roman Senate turns to Marcus Crassus, a wealthy, strategic politician, for aid. He respects his opponent and refuses to make the same mistake Glaber and his predecesors have. With a young and fiercely competitve Julius Caesar as an ally, Crassus is determined to crush Spartacus and his rebellion. The epic conclusion of a legendary journey, Spartacus: War of the Damned unleashes a battle unlike anything ever seen before.

Spartacus continues to build a formidable army and outwit Rome's best commanders. The powers of the Empire are forced to turn to wealthy, ambitious Marcus Crassus to aid the campaign.

Spartacus leads a daring assault to provide food and shelter for his people. Crassus builds a fearsome army and receives an unexpected visitor.

Spartacus considers striking a deal with a band of marauders to ensure his people stay supplied and fed. Crassus's son Tiberius makes a bold and fateful decision.

The possible infiltration of a Roman spy causes tension between Spartacus and his men. Crassus resurrects a long abandoned form of Roman punishment to teach his soldiers a brutal lesson.

Spartacus puts a plan in motion to weaken Crassus's forces and gain the upper hand. Betrayal threatens to foil the plan.

As Crassus leads an onslaught against the rebel-occupied city, Gannicus is trapped behind enemy lines. Tiberius is tasked by Crassus to hold a celebration in honor of a man he despises.

Their forces trapped on an impassable ridge, Spartacus and Crixus clash over the method of escape. Crassus has increasing difficulty controlling the actions of those closest to him.

Spartacus and the rebels arrive at a crossroads. With the relentless Crassus driving his men hard in the pursuit of Spartacus, the conflict between Tiberius and Caesar escalates.

Crassus learns that a fellow prominent Roman is attempting to steal the glory of defeating Spartacus. Spartacus aims to secure a bargaining chip he can use against the Romans.

Spartacus and his outnumbered rebels make one last attempt to win freedom in an epic final battle against the Romans.